Typically, to achieve better performance, especially in gaming and graphics-heavy tasks, you should keep the hardware-accelerated GPU scheduling turned on. The main reason is that it gives the GPU the ability to schedule its own work, thereby freeing up the CPU to do other tasks, resulting in reduced CPU overhead, better frame pacing, and lower input lag. Nevertheless, the increase in performance is generally very limited and depends on the configurations of your hardware and drivers. Sometimes, it might even lead to stuttering or other issues with compatibility, in which case it would be better to turn it off. Generally, it is a good idea to have it enabled, check the performance, and then turn it off if you experience any instability, crashes, or degraded performance.